Studies have shown that over-the-counter NSAID pain killers like Ibuprofen, diclofenac, celecoxib, and naproxen can potentially cause users to have a heart attack or a stroke. New labeling being required by the US Food and Drug Administration on the packaging of NSAIDS will warn users of these possible side effects, along with advising them that their risk of heart failure is increased if they take these drugs. The new labels will include the fact that these heart problems can occur as soon as the initial weeks of use of the NSAIDS. They will also say that heart failure, heart attack, and stroke can affect people using NSAIDS who have no history of heart issues, and no genetic predisposition toward heart disease. People who already have heart issues or who have certain risk factors for heart disease have a higher probability of suffering heart failure, heart attacks, or strokes with NSAID usage, though. Studies seem to show that higher doses of NSAIDS increase possible heart failure or damage. NSAIDS have been used for years to treat fever as well as the pain from arthritis, headaches, abdominal cramping, and the discomfort from viral diseases.